Endometrial Receptivity Assay

What is the ERA test?


The ERA test uses a sample of endometrial cells (cells in the lining of the uterus) at a specific time in the menstrual cycle to evaluate a pattern of gene expression that helps us determine if the endometrium is ‘ready’ for implantation.  We call this a ‘receptive endometrium’, meaning that an embryo is likely to implant and grow into a healthy pregnancy.  Naturally, there is a very narrow window of implantation, so it is important in many cases to make sure we have identified the exact right time to perform an embryo transfer and allow for implantation to take place.  

Who is the ERA test for?


This test is used in cases of recurrent implantation failure with In Vitro Fertilization, of either morphologically good embryos or chromosomally screen embryos (“PGS-tested”).  In some cases of patients who have had implantation failure, the receptivity test has shown us that the embryo transfer would be most successful either earlier or later than would otherwise would be standard.  Changing the timing of the embryo transfer can make the difference of having a successful pregnancy or not.  


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