Endometrial Receptivity Assay (ERA) Testing in New Jersey
Endometrial Receptivity Assay/Analysis Test
The Endometrial Receptivity Assay/Analysis Test (ERA test) uses a sample of endometrial cells – the cells that make up the lining of the uterus – to define the optimum time for embryo implantation during IVF. This test is an excellent tool in improving the chances for successful embryo implantation, especially in patients who have experienced failed IVF implantation in South Jersey.
How the ERA Test Works
The ERA test is performed during a specific time in the menstrual cycle to evaluate a pattern of gene expression that can help determine if the endometrium is ‘ready’ for implantation. We call this a ‘receptive endometrium’, meaning that an embryo is likely to implant and grow into a healthy pregnancy. Most women experience a window of implantation 8-10 days after ovulation, however, research suggests that some women may have a personal window of implantation. Therefore, when conventional timing is used for women with a personal window (also known as a displaced window), they are less likely to experience a successful implantation.
The ERA test works by a fertility specialist taking a biopsy of the uterine lining after medication (medications like progesterone are used in embryo transfers to make the uterine lining thicker and more receptive to an embryo) has been administered for 5 days, or more depending on the uterine lining measurements. The ERA is done on the day an embryo transfer would normally occur, except instead of transferring an embryo, the biopsy is taken. These cells are analyzed and the test can then predict if the endometrium would be receptive or non-receptive. If receptive, then this is the best timing to apply to a future month for implantation. If non-receptive, the patient and doctor now know that the window of implantation is in fact displaced, and can adjust timing accordingly to find the correct window through future ERA testing.
Naturally, there is a very narrow window of embryo implantation, so it is important in many cases to make sure we have identified the exact right time to perform an embryo transfer and allow for implantation to take place.
When to Consider an ERA Test
This test is used in cases of recurrent implantation failure with In Vitro Fertilization, of healthy embryos or even chromosomally screened embryos (“PGS-tested”). In some cases of patients who have had implantation failure, the receptivity test has shown us that the embryo transfer would be most successful either earlier or later than would otherwise would be standard. Changing the timing of the embryo transfer can make all the difference of having a successful pregnancy or not.
South Jersey IVF Specialists and ERA Testing
The IVF specialists at South Jersey Fertility Center are highly experienced in helping patients achieve their dream of building a family. We provide comprehensive fertility services including ERA testing to give our patients their highest chances of achieving a successful pregnancy. We serve patients in New Jersey and Pennsylvania through our conveniently located offices in Marlton, Burlington, Sewell, and Egg Harbor Township. We are easily accessible to patients in Burlington, Mercer, Atlantic, Camden, Ocean and Bucks Counties.